Human peripheral blood lymphocytes are stained with APC Anti-Human CD19 Antibody and FITC Anti-Human CD185/CXCR5 Antibody (Left). Lymphocytes are stained with APC Anti-Human CD19 Antibody and FITC Mouse IgG1,κ Isotype Control (Right).
CD185, also known as CXCR5, is a 42 kD G-protein coupled receptor with seven transmembrane regions. CXCR5 is expressed by mature B cells, follicular helper T cells, Burkitt’s lymphoma cells and a subset of neurons, and mediates cell migration to the B cell follicles in the secondary lymphoid organs. The ligand of CXCR5 is CXCL13 (BLC).
Immunogen Information
Gene ID
643
Synonyms
CXCR5C-X-C chemokine receptor type 5Burkitt lymphoma receptor 1BLR1Monocyte-derived receptor 15MDR15
