Western blot with HRP-conjugated Vinculin Monoclonal Antibody at dilution of 1:5000.lane 1:Raji whole cell lysate, lane 2:HL-60 whole cell lysate, lane 3:U87-MG whole cell lysate, lane 4:mouse lung whole cell lysate, lane 5:rat lung whole cell lysate, lane 6:C6 whole cell lysate
Vinculin belongs to the vinculin/alpha-catenin family. It is an actin filament (F-actin)-binding protein which involved in cell-matrix adhesion and cell-cell adhesion. Vinculin regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. It may also play important roles in cell morphology and locomotion. Vinculin is a 117-kDa, 1, 066-amino-acid protein which is ubiquitously expressed. Its splice variant, metavinculin (124 kDa), is muscle-specific.
Immunogen Information
Immunogen
Recombinant Human Vinculin protein expressed by E.coli
