Mcl-1 Monoclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
Immunohistochemistry of paraffin-embedded human breast carcinoma using Mcl-1 Monoclonal Antibody at dilution of 1:30.
Immunohistochemistry of paraffin-embedded human breast carcinoma using Mcl-1 Monoclonal Antibody at dilution of 1:30.
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Overview

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Product Name
Mcl-1 Monoclonal Antibody
Catalog Number
RD269210A
Clonality
Monoclonal
Purification Method
Protein A purification
Isotype
IgG1
Host

Background

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This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 0) promote apoptosis and are death-inducing.

Immunogen Information

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Immunogen
A synthetic peptide corresponding to the center region of the Human Mcl-1
Swissprot
Q07820
Synonyms
BCL2Lbcl2-LMCLMCL1BCL2L3EATMCL1-ESMCL1LMCL1SMcl-1TMbcl2-L-3mcl1/EATBcl 2 related protein EAT/mcl1BCL2 relatedBcl-2-like protein 3Bcl-2-related protein EAT/mcl1Induced myeloid leukemia cell differentiation protein Mcl 1Induced myeloid leu

Applications

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Reactivity
Tested Applications
Conjugation
Unconjugated
Dilution
IHC-P 1:20-1:80;
Concentration
1 mg/mL
Storage Buffer
0.2 μm filtered solution in PBS
Storage Instructions
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

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