CD45 Monoclonal Antibody

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Catalog NumberRD85467A

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Overview
Product NameCD45 Monoclonal Antibody
Catalog NumberRD85467A
Purification MethodProtein A purification
IsotypeIgG
HostMouse
Clone NumberClone:3H3
Background

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling.

Immunogen Information
ImmunogenSynthetic Peptide
SwissprotP08575
SynonymsB220CD 45CD45CD45 antigenCD45RGP180L-CALCALeukocyte common antigenlocLy-5LY5Ly5homolog ofLyt-4OTTHUMP00000033813OTTHUMP00000033816OTTHUMP00000033817OTTHUMP00000038574Protein tyrosine phosphatase receptor type c polypeptidereceptor type Cprotein tyrosine phosphataseCProtein tyrosine phosphatasereceptor typec polypeptidePtprcPTPRCReceptor-type tyrosine-protein phosphatase CT200T200 glycoproteinT200 leukocyte common antigen
Applications
ReactivityHuman
Tested applicationsWB,IHC-p
ConjugationUnconjugated
DilutionWB 1:500-1:2000, IHC 1:50-300
Dilution1 mg/mL
Storage BufferPBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Storage InstructionsStore at -20°C. Avoid freeze / thaw cycles.
Research Area

Cancer, Cardiovascular, Immunology, Neuroscience, Signal Transduction, Stem Cells

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