(KO Validated) EGFR Polyclonal Antibody

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Catalog NumberRD80636A

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Overview
Product Name(KO Validated) EGFR Polyclonal Antibody
Catalog NumberRD80636A
Purification MethodAffinity purification
IsotypeIgG
HostRabbit
Background

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.

Immunogen Information
ImmunogenRecombinant fusion protein of human EGFR (NP_005219.2).
Gene ID1956
SwissprotP00533
SynonymsEGFRERBBERBB1HER1mENANISBD2PIG61
Applications
ReactivityHuman,Mouse,Rat
Tested applicationsWB,IF
ConjugationUnconjugated
DilutionWB 1:500-1:2000 IF 1:50-1:200
Dilution1 mg/mL
Storage BufferPBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage InstructionsStore at -20°C. Avoid freeze / thaw cycles.
Research Area

Cancer, Signal Transduction

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