This gene is encodes a mitochondrial protein that contains a BH3 domain and acts as a pro-apoptotic factor. The encoded protein interacts with anti-apoptotic proteins, including the E1B 19 kDa protein and Bcl2. This gene is silenced in tumors by DNA methylation.
Immunogen Information
Immunogen
Recombinant Human BNIP-3 protein
Swissprot
Q12983
Synonyms
NIPBNIPBNIP3NIP3BCL2/Adenovirus E1B 19 kDa Protein-Interacting Protein 3BNIP-3