Western Blot with MSH2 Monoclonal Antibody at dilution of 1:1000. Lane 1: HeLa
Immunohistochemistry of paraffin-embedded Human esophagus using MSH2 Monoclonal Antibody at dilution of 1:50.
Immunohistochemistry of paraffin-embedded Human tonsil using MSH2 Monoclonal Antibody at dilution of 1:50.
Immunoprecipitation analysis using anti-MSH2 Monoclonal Antibody. Western blot was performed from the immunoprecipitate using MSH2 Monoclonal Antibody at a dilution of 1:100. Lane 1: 5% Input, Lane 2: Rabbit monoclonal IgG Isotype, Lane 3: MSH2 Monoclonal Antibody
This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.
