Recombinant Phospho-Tau (Ser202, Thr205) Monoclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
Western blot analysis of extracts from mouse brain (line A); treated with antigen-specific phosphopeptide (line B) or antigen-specific peptide (line C) using Phospho-Tau (Ser202, Thr205) rabbit monoclonal Antibody  at 1:2000 dilution.. (Validation Experiment)
Western blot analysis of extracts from mouse brain (line A); treated with antigen-specific phosphopeptide (line B) or antigen-specific peptide (line C) using Phospho-Tau (Ser202, Thr205) rabbit monoclonal Antibody at 1:2000 dilution.. (Validation Experiment)
Western blot analysis of extracts from rat brain using Phospho-Tau (Ser202, Thr205) rabbit monoclonal Antibody  at 1:5000 dilution..
Western blot analysis of extracts from rat brain using Phospho-Tau (Ser202, Thr205) rabbit monoclonal Antibody at 1:5000 dilution..
Western blot analysis of 200 ng Recombinant Human Tau Protein (Full Length)  (line A) and 200 ng Recombinant Human Tau Protein (Full Length), GSK3beta-phosphorylated  (line B) using Phospho-Tau (Ser202, Thr205) Rabbit Monoclonal Antibody  at 1:5000 dilution..
Western blot analysis of 200 ng Recombinant Human Tau Protein (Full Length) (line A) and 200 ng Recombinant Human Tau Protein (Full Length), GSK3beta-phosphorylated (line B) using Phospho-Tau (Ser202, Thr205) Rabbit Monoclonal Antibody at 1:5000 dilution..
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Overview

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Product Name
Recombinant Phospho-Tau (Ser202, Thr205) Monoclonal Antibody
Catalog Number
RD269774A
Clonality
Monoclonal
Purification Method
Protein A purification
Isotype
IgG

Background

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This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.

Immunogen Information

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Immunogen
A synthetic phosphopeptide corresponding to residues around
Swissprot
P10636
Synonyms
FTDPPPP1RDDPACFTDP-17MAPTLMSTDMTBT1MTBT2PPNDPPP1R103TAUMAPTMicrotubule-Associated Protein TauNeurofibrillary Tangle ProteinPaired Helical Filament-TauPHF-TaupMAPT/pTAUTAU and MAPTN/AAI413597AW045860FLJ31424FTDP 17G protein beta1/gam
Calculated MW
78 kDa
Observed MW
50-80 kDa

Applications

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Reactivity
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:2000-1:10000
Concentration
1 mg/mL
Storage Buffer
10 mM sodium HEPES; 150 mM NaCl; 100 μg/mL protein protectant; 50% glycerol; pH 7.5
Storage Instructions
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

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