Western Blot with Thymidylate Synthase Monoclonal Antibody at dilution of 1:1000. Lane 1: HeLa, Lane 2: Jurkat, Lane 3: Raw264.7, Lane 4: 293T, Raji
Immunohistochemistry of paraffin-embedded Human colon cancer using Thymidylate Synthase Monoclonal Antibody at dilution of 1:1000.
Immunohistochemistry of paraffin-embedded Human ovarian cancer using Thymidylate Synthase Monoclonal Antibody at dilution of 1:100.
Immunoprecipitation analysis using anti-Thymidylate Synthase Monoclonal Antibody. Western blot was performed from the immunoprecipitate using Thymidylate Synthase Monoclonal Antibody at a dilution of 1:100. Lane 1: 5% Input, Lane 2: Thymidylate Synthase Monoclonal Antibody, Lane 3: Rabbit monoclonal IgG Isotype
Thymidylate synthase (TS) is a key enzyme in the synthesis of 2'-deoxythymidine-5'-monophosphate, an essential precursor for DNA biosynthesis. Thymine nucleotide synthase is a key enzyme in the de novo synthesis pathway of mitochondrial thymine. For this reason, it is a key target for cancer chemotherapy, and considered to be the main target of 5-fluorouric acid, 5-fluoro-2'-deoxyribonucleic acid and some folate compounds.
