Apoptosis Detection Kits 

Apoptosis, or programmed cell death, plays a vital role in development, immune regulation, and disease progression. Accurate detection and quantification of apoptotic cells are essential in a wide range of biological and medical research applications. Our Annexin V-based Apoptosis Assay Kits provide reliable, easy-to-use solutions for identifying apoptotic and necrotic cells using flow cytometry.

These kits leverage the high affinity of Annexin V for phosphatidylserine—a key apoptotic marker that becomes externalized on the cell membrane during early apoptosis. Paired with viability dyes such as propidium iodide (PI) or 7-AAD, these assays distinguish between live, early apoptotic, late apoptotic, and necrotic cells with high specificity and sensitivity.

Key Features:

• Clear discrimination of live, apoptotic, and necrotic cell populations
• Optimized for flow cytometry applications
• Wide range of fluorescent labels compatible with common laser and filter sets
• Fast and simple protocols

Available Products:

• Annexin V-FITC/PI Apoptosis Detection Kit
  Classic green fluorescence detection of early apoptosis using FITC-labeled Annexin V and PI for necrosis.
• Annexin V-eGFP/PI Apoptosis Detection Kit
  Combines enhanced green fluorescence (eGFP) with PI for robust apoptotic and necrotic cell detection.
• Annexin V-Reddot Fluor 488/PI Apoptosis Detection Kit
  Features Reddot Fluor 488, a bright green dye alternative to FITC, with PI for dual-color apoptosis analysis.
• Annexin V-Reddot Fluor 647/PI Apoptosis Detection Kit
  Uses far-red Reddot Fluor 647 for reduced spectral overlap and compatibility with multi-color flow cytometry panels.
• Annexin V-PE/7-AAD Apoptosis Detection Kit
  Utilizes PE (phycoerythrin) and 7-AAD for powerful red and far-red emission profiles—ideal for complex multiparametric analyses.

Applications:

Our Annexin V Apoptosis Detection Kits are ideal for use in:

• Cancer research: Evaluate tumor cell response to chemotherapeutic agents
• Drug screening: Measure apoptotic effects of new compounds on target cells
• Immunology: Study T-cell activation and immune cell death
• Neuroscience: Analyze neuronal cell death in response to injury or disease
• Toxicology: Assess cytotoxicity and safety of chemicals or biologics
• Cell biology: Investigate cell cycle dynamics and stress-induced apoptosis
• Stem cell research: Monitor viability and differentiation processes

Check out our collection of Apoptosis Detection Kits!

Contact our support team here with any questions, or if you need help selecting which product is right for you.