ABCG2 Polyclonal Antibody
Catalog Number
RD70724A
Western Blot analysis of HT-29 cells with ABCG2 Polyclonal Antibody.
Variation
Quantity
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Overview
Product Name
ABCG2 Polyclonal Antibody
Catalog Number
RD70724A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. May be involved in brain-to-blood efflux. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123.
Immunogen Information
Immunogen
Synthesized peptide derived from the Internal region of human ABCG2.
Swissprot
Q9UNQ0
Synonyms
ABC transporterABC15ABCG 2ABCG2ABCG2ABCPATP binding cassette sub family G (WHITE) member 2ATP binding cassette transporter G2ATP-binding cassette sub-family G member 2BCRPBCRP1BMDPBreast cancer resistance proteinCD338CDw338CDw338 antigenES
Calculated MW
72 kDa
Observed MW
72 kDa
Applications
Reactivity
Human
Tested Applications
WB,IHC-p,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.