ACOD1 Polyclonal Antibody
Catalog Number
RD219833A
Western blot analysis of Mouse heart tissue and K562 cell lysates using ACOD1 Polyclonal Antibody at dilution of 1:400
Variation
Quantity
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Overview
Product Name
ACOD1 Polyclonal Antibody
Catalog Number
RD219833A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
Involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs)-mediated inflammatory innate response by stimulating the tumor necrosis factor alpha-induced protein TNFAIP3 expression via reactive oxygen species (ROS) in LPS-tolerized macrophages. Involved in antimicrobial response of innate immune cells; ACOD1-mediated itaconic acid production contributes to the antimicrobial activity of macrophages. Plays a role in the embryo implantation.
Immunogen Information
Immunogen
Synthetic peptide of human ACOD1
Swissprot
A6NK06
Synonyms
ACOD1Aconitate decarboxylase 1Aconitate decarboxylaseCADCis aconitate decarboxylaseImmune responsive gene 1 protein homologImmune-responsive gene 1 protein homologImmunoresponsive 1 homolog (mouse)Irg1IRG1OC116OPTB1TCTIRC7
Calculated MW
53 kDa
Observed MW
Refer to figures
Gene Accession
NP001245335
Applications
Reactivity
Human, Mouse
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, ELISA 1:5000-1:10000
Concentration
1.32 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas