AF/LE Purified Anti-Mouse CD117 Antibody
Catalog Number
RD21050F
Variation
Quantity
For more information on our kits, please contact us at info@reddotbiotech.com
Overview
Product Name
AF/LE Purified Anti-Mouse CD117 Antibody
Catalog Number
RD21050F
Clonality
Monoclonal
Isotype
Rat IgG2b, κ
Host
Rat
Background
CD117 is a 145 kD immunoglobulin superfamily member also known as c-Kit and stem cell factor receptor (SCFR). It is a transmembrane tyrosine-kinase receptor that binds the c-Kit ligand (also known as steel factor, stem cell factor, and mast cell growth factor). CD117 is expressed on hematopoietic stem cells (including multipotent hematopoietic stem cells, progenitors committed to myeloid and/or erythroid lineages, and T and B cell precursors), mast cells, and acute myeloid leukemia (AML) cells. CD117 interaction with its ligand is critical for the development of hematopoietic stem cells.
Immunogen Information
Gene ID
16590
Swissprot
P05532
Synonyms
Mast/stem cell growth factor receptor KitKitSCFRProto-oncogene c-KitTyrosine-protein kinase KitCD117
Applications
Reactivity
Mouse
Tested Applications
FCM
Conjugation
None (Purified antibody-Azide Free/Low endotoxin)
Concentration
0.5 mg/mL
Storage Buffer
0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Storage Instructions
Store at 2~8°C. Do not freeze.