AKR1C2 Polyclonal Antibody
Catalog Number
RD265772A
Western blot analysis of extracts of various cell lines using AKR1C2 Polyclonal Antibody at dilution of 1:1000.
Immunofluorescence analysis of L929 cells using AKR1C2 Polyclonal Antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Immunofluorescence analysis of U-2 OS cells using AKR1C2 Polyclonal Antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Variation
Quantity
For more information on our kits, please contact us at info@reddotbiotech.com
Overview
Product Name
AKR1C2 Polyclonal Antibody
Catalog Number
RD265772A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene.
Immunogen Information
Immunogen
Recombinant fusion protein of human AKR1C2 (NP_995317.1).
Gene ID
1646
Swissprot
P52895
Synonyms
AKR1C2AKR1C-pseudoBABPDDDD-2DD/BABPDD2DDH2HAKRDHBABMCDR2SRXY8TDD
Calculated MW
15 kDa/36 kDa
Observed MW
37 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IF
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000 IF 1:50-1:100
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas