APC Anti-Mouse CD45 Antibody
Catalog Number
RD21679F
C57BL/6 murine splenocytes are stained with Anti-Mouse CD45 Monoclonal Antibody(APC Conjugated)(filled gray histogram). Unstained splenocytes (empty black histogram) are used as control.
Variation
Quantity
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Overview
Product Name
APC Anti-Mouse CD45 Antibody
Catalog Number
RD21679F
Clonality
Monoclonal
Isotype
Rat IgG2b, κ
Host
Rat
Background
CD45 is a 180-240 kD glycoprotein also known as the leukocyte common antigen (LCA), T200, or Ly-5. It is a member of the protein tyrosine phosphatase (PTP) family, expressed on all hematopoietic cells except mature erythrocytes and platelets. There are different isoforms of CD45 that arise from alternative splicing of exons 4, 5, and 6, which encode A, B, and C determinants, respectively. CD45 plays a key role in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation state of the cell as well as cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.
Immunogen Information
Gene ID
19264
Swissprot
P06800
Synonyms
Receptor-type tyrosine-protein phosphatase CPtprcL-CALy-5T200CD45
Applications
Reactivity
Mouse
Tested Applications
FCM
Conjugation
APC
Storage Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Instructions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.