APPL1 Polyclonal Antibody
Catalog Number
RD83116A
Western blot analysis of extracts of various cell lines using APPL1 Polyclonal Antibody at dilution of 1:1000.
Variation
Quantity
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Overview
Product Name
APPL1 Polyclonal Antibody
Catalog Number
RD83116A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus.
Immunogen Information
Immunogen
Recombinant fusion protein of human APPL1 (NP_036228.1).
Gene ID
26060
Swissprot
Q9UKG1
Synonyms
APPL1APPLDIP13alphaMODY14
Calculated MW
79 kDa
Observed MW
95 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.