BABAM2 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Western Blot analysis of A431 using BABAM2 Polyclonal Antibody at dilution of 1:750
Immunohistochemistry of paraffin-embedded Human liver cancer using BABAM2 Polyclonal Antibody at dilution of 1:40
Immunohistochemistry of paraffin-embedded Human thyroid cancer using BABAM2 Polyclonal Antibody at dilution of 1:40
Product Name
BABAM2 Polyclonal Antibody
Catalog Number
RD211008A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Brain and reproductive organ-expressed protein (BRE) is a 415 amino acid protein which binds to the intracellular juxtamembrane domain of the death receptor, tumor necrosis factor receptor 1 (TNF-R1). BRE also binds to the death receptor, FAS. BRE downregulates TNFa-induced activation of NFkB and may play a role in homeostasis or cellular differentiation in cells of epithelial, neural and germ line origins. It inhibits components of the death-inducing signaling complexes that are necessary for activation of the mitochondria, thereby mediating apoptosis. BRE is strongly expressed in the adrenal cortex, medulla, testis and pancreas, and is weakly expressed in the thymus, thyroid, stomach and small intestine.
Immunogen Information
Immunogen
Recombinant protein of human BRE
Swissprot
Q9NXR7
Synonyms
6030405P19RikAI429776B830038C02RikBrain and reproductive organ expressed (TNFRSF1A modulator)brain and reproductive organ expressed proteinBrain and reproductive organ-expressed proteinBRCA1 A complex subunit BREBRCA1-A complex subunit BREBRCA1/BR
Calculated MW
44 kDa
Gene Accession
BC001251
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Concentration
0.5 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas