BCL2 Monoclonal Antibody
Catalog Number
RD85462A
Western Blot analysis of Hela cells using BCL2 Monoclonal Antibody at dilution of 1:1000.
Immunohistochemistry of paraffin-embedded Human tonsil tissue using BCL2 Monoclonal Antibody at dilution of 1:200.
Variation
Quantity
For more information on our kits, please contact us at info@reddotbiotech.com
Overview
Product Name
BCL2 Monoclonal Antibody
Catalog Number
RD85462A
Clonality
Monoclonal
Purification Method
Protein A purification
Isotype
IgG
Host
Mouse
Background
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
Immunogen Information
Immunogen
Synthetic Peptide
Swissprot
P10415
Synonyms
Apoptosis regulator Bcl 2Apoptosis regulator Bcl-2Apoptosis regulator Bcl2AW986256B cell CLL/lymphoma 2B cell leukemia/lymphoma 2Bcl-2Bcl2BCL2C430015F12RikD630044D05RikD830018M01RikLeukemia/lymphomaB-cell2Oncogene B-cell leukemia 2PPP1R50
Calculated MW
26 kDa
Observed MW
26 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC-p
Conjugation
Unconjugated
Dilution
WB 1:1000-2000, IHC 1:50-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas