TUBB3,the class III β tubulin or Tuj1,is selectively expressed in testis and neurons of the central and peripheral nervous system. It has been widely used as a marker for neurons. Aberrant expression of TUBB3 has also been found in various tumors of non-neural origin and can be used as a biomarker for cancer aggressiveness and a marker for the tendency to respond poorly to chemotherapy. This antibody is specific to TUBB3 but not cross-react with other tubulin isoforms.
Immunogen Information
Immunogen
Synthesized peptide derived from the C-terminal region of mouse Tubulin β
Swissprot
Q13509
Synonyms
beta 3 tubulinbeta-4CDCBMCDCBM1CFEOM3CFEOM3AFEOM3M(beta)3M(beta)6MC1RNeuron specific beta III TubulinNeuron-specific class III beta-tubulinQccE-11995QccE-15186TBB3Tubb 3TUBB3TUBB4Tubulin beta 3Tubulin beta 3 chainTubulin beta 4Tubulin
Calculated MW
50 kDa
Observed MW
55 kDa
Applications
Reactivity
Mouse,Rat
Tested Applications
WB,IHC-p,IF,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4