BMP2 Polyclonal Antibody
Catalog Number
RD70320A
Western Blot analysis of various samples using BMP2 Polyclonal Antibody at dilution of 1:1000.
Immunohistochemistry analysis of paraffin-embedded mouse bone marrow using BMP2 Polyclonal Antibody at dilution of 1:300.
Variation
Quantity
For more information on our kits, please contact us at info@reddotbiotech.com
Overview
Product Name
BMP2 Polyclonal Antibody
Catalog Number
RD70320A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Bone morphogenetic protein-2 (BMP-2) is a member of the transforming growth factor-beta (TGFB) superfamily. BMP2 is synthesized as a 60 kDa precursor that is processed in the secretory pathway to a small 18 kDa monomer; 2 monomers then associate to form the active 30 kDa homodimer,which binds to its receptor. There is also a 40-45 kDa form of BMP2,as an amino-terminal propeptide. BMP2 can induce bone formation and regeneration during early embryonic development. It is involved in the hedgehog pathway,TGF beta signaling pathway,and cytokine-cytokine receptor interaction.
Immunogen Information
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse BMP2
Swissprot
P12643,P21274,P49001
Synonyms
BDA2BMP-2BMP-2ABmp2BMP2BMP2ABone morphogenetic protein 2Bone morphogenetic protein 2A
Calculated MW
45 kDa
Observed MW
45 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:200-1:800
Concentration
2.4 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas