C5AR1 Polyclonal Antibody
Catalog Number
RD218573A
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using C5AR1 Polyclonal Antibody at dilution of 1:50(×200)
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using C5AR1 Polyclonal Antibody at dilution of 1:50(×200)
Variation
Quantity
For more information on our kits, please contact us at info@reddotbiotech.com
Overview
Product Name
C5AR1 Polyclonal Antibody
Catalog Number
RD218573A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events (PubMed:8182049, PubMed:7622471, PubMed:9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production (PubMed:10636859, PubMed:15153520).
Immunogen Information
Immunogen
Fusion protein of human C5AR1
Swissprot
P21730
Synonyms
ANAPHYLATOXIN RECEPTORC5a anaphylatoxin chemotactic receptorC5a anaphylatoxin receptorC5AC5a ligandC5a-RC5aRC5ARc5ar1C5R1CD88CD88 antigenComplement component 5 receptor 1Complement component 5 receptor 2Complement component 5a receptor 1
Gene Accession
BC008982
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:40-1:200, ELISA 1:5000-1:10000
Concentration
0.7 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas