CASP7 Polyclonal Antibody
Catalog Number
RD70879A
Western Blot analysis of HT29 cells using CASP7 Polyclonal Antibody at dilution of 1:1000.
Variation
Quantity
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Overview
Product Name
CASP7 Polyclonal Antibody
Catalog Number
RD70879A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-Gly-217' bond. Overexpression promotes programmed cell death.
Immunogen Information
Immunogen
Synthesized peptide derived from the N-terminal region of human Caspase-7.
Swissprot
P55210
Synonyms
Apoptotic protease Mch-3Apoptotic protease MCH3CASP-7CASP7CASP7Caspase 7Caspase 7 apoptosis related cysteine peptidaseCaspase-7 subunit p11Caspase7CMH 1CMH-1CMH1ICE LAP3ICE-LAP3ICE-like apoptotic protease 3LICE2MCH3
Calculated MW
34 kDa
Observed MW
35 kDa
Applications
Reactivity
Human
Tested Applications
WB,IHC-p,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, ICC 1:200-1:1000, ELISA 1:5000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas