CASP8 Polyclonal Antibody
Catalog Number
RD219664A
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CASP8 Polyclonal Antibody at dilution of 1:35(×200)
Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CASP8 Polyclonal Antibody at dilution of 1:35(×200)
Variation
Quantity
For more information on our kits, please contact us at info@reddotbiotech.com
Overview
Product Name
CASP8 Polyclonal Antibody
Catalog Number
RD219664A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
Caspase 8,also named as MCH5,MACH,FLICE,and CAP4,belongs to the peptidase C14A family. It may participate in the GZMB apoptotic pathways and functions as an upstream regulator in a-bisabolol-induced apoptosis. Caspase 8 catalyzes an essential intermediate step in the ubiquitination and proteasome-mediated degradation of IRF3. It may control diabetic embryopathy-associated apoptosis via Caspase 8 is expressed as nine isoforms by alternative splicing with the molecular mass from 26 kDa to 62 kDa. Caspase 8 Monoclonal Antibody can recognize pro- and cleaved-caspase 8.
Immunogen Information
Immunogen
Synthetic peptide of human CASP8
Swissprot
Q14790
Synonyms
ALPS2BAmyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 proteinApoptotic cysteine proteaseApoptotic protease Mch-5Apoptotic protease Mch5CAP4CASP-8CASP8CASP8Caspase 8Caspase 8 apoptosis related cysteine peptidaseCaspase-8 sub
Gene Accession
NP203519
Applications
Reactivity
Human, Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:30-1:150, ELISA 1:5000-1:10000
Concentration
0.5 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas