CAV1 Polyclonal Antibody

Catalog Number
RD70891A
Western Blot analysis of various cells using CAV1 Polyclonal Antibody at dilution of 1:1000.
Western Blot analysis of various cells using CAV1 Polyclonal Antibody at dilution of 1:1000.
Immunohistochemistry of paraffin-embedded Human stomach tissue using CAV1 Polyclonal Antibody at dilution of 1:200.
Immunohistochemistry of paraffin-embedded Human stomach tissue using CAV1 Polyclonal Antibody at dilution of 1:200.
Immunofluorescence analysis of Rat kidney tissue using CAV1 Polyclonal Antibody at dilution of 1:200.
Immunofluorescence analysis of Rat kidney tissue using CAV1 Polyclonal Antibody at dilution of 1:200.
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Overview
Circle
Product Name
CAV1 Polyclonal Antibody
Catalog Number
RD70891A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Circle
May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway.
Immunogen Information
Circle
Immunogen
Synthesized peptide derived from the C-terminal region of human Caveolin-1
Swissprot
Q03135
Synonyms
BSCL3CAVCAV1CAV1caveolae protein22 kDcaveolin 1 alpha isoformcaveolin 1 beta isoformCaveolin 1 caveolae protein 22kDaCaveolin-1Caveolin1cell growth-inhibiting protein 32CGL3LCCNSMSTP085OTTHUMP00000025031PPH3VIP 21VIP21
Calculated MW
20 kDa
Observed MW
25 kDa
Applications
Circle
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC-p,IF,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-2000, IHC 1:50-300, IF 1:50-300
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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