CD137 Polyclonal Antibody
Catalog Number
RD79900A
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using CD137 Polyclonal Antibody at dilution 1:50
Variation
Quantity
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Overview
Product Name
CD137 Polyclonal Antibody
Catalog Number
RD79900A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.
Immunogen Information
Immunogen
Recombinant protein of human TNFRSF9
Swissprot
Q07011
Synonyms
4 1BB4 1BB ligand receptor4-1BB ligand receptor4-1BB Ligand Receptor T Cell4-1BBmousehomolog ofAntigen 4-1BB HomologCD 137CD137CD137 antigenCDw137HLDA VIHomolog of mouse 4 1BBILAinduced by lymphocyte activation (ILA)Induced by lymphocyte a
Gene Accession
BC006196
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.7 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas