CD284 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD70565A
Western Blot analysis of various samples using CD284 Polyclonal Antibody at dilution of 1:1000.
Immunohistochemistry analysis of paraffin-embedded mouse spleen using CD284 Polyclonal Antibody at dilution of 1:1000.
Immunohistochemistry analysis of paraffin-embedded rat lymph using CD284 Polyclonal Antibody at dilution of 1:1000.
Variation
Quantity
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Overview
Product Name
CD284 Polyclonal Antibody
Catalog Number
RD70565A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
TLR4,also named as CD284,belongs to the Toll-like receptor family. TLR4 cooperates with LY96 and CD14 to mediates the innate immune response to bacterial lipopolysaccharide (LPS). TLR4 acts via MYD88,TIRAP and TRAF6,leading to NF-kappa-B activation,cytokine secretion and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described.
Immunogen Information
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse TLR4.
Swissprot
O00206,Q9QUK6,Q9QX05
Synonyms
ARMD10CD284CD284 antigenHomolog of Drosophila tollhTollTLR 4TLR4TLR4TOLLToll like receptor 4Toll-like receptor 4
Calculated MW
95 kDa
Observed MW
95 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1::500-1:2000
Concentration
0.9 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas