CD86 Polyclonal Antibody
Catalog Number
RD240090A
Immunohistochemistry of paraffin-embedded Rat brain using CD86 Polyclonal Antibody at dilution of 1:50
Variation
Quantity
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Overview
Product Name
CD86 Polyclonal Antibody
Catalog Number
RD240090A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation.
Immunogen Information
Immunogen
Recombinant humanT-lymphocyte activation antigen CD86 protein
Swissprot
P42081
Synonyms
Activation B7-2 antigen 3Activation B7-2 antigenB-lymphocyte activation antigen B7-2 2B-lymphocyte activation antigen B7-2B7 2B7B7-2B7.2B70B72 antigenBU63CD28 antigen ligand 2 2CD28 antigen ligand 2Cd28l2CD28LG2CD86CD86 antigenCD86 antige
Applications
Reactivity
Rat
Tested Applications
IHC
Conjugation
Unconjugated
Dilution
IHC 1:50-1:100
Concentration
2 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas