CFH Polyclonal Antibody
Catalog Number
RD82573A
Immunohistochemistry of paraffin-embedded Human liver damage using CFH Polyclonal Antibody at dilution of 1:200 (40x lens).
Immunohistochemistry of paraffin-embedded Human liver cancer using CFH Polyclonal Antibody at dilution of 1:200 (40x lens).
Variation
Quantity
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Overview
Product Name
CFH Polyclonal Antibody
Catalog Number
RD82573A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Immunogen Information
Immunogen
Recombinant fusion protein of human CFH (NP_001014975.1).
Gene ID
3075
Swissprot
P08603
Synonyms
CFHAHUS1AMBP1ARMD4ARMS1CFHL3FHFHL1HFHF1HF2HUS
Applications
Reactivity
Human
Tested Applications
IHC
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas