CFL1 Polyclonal Antibody
Catalog Number
RD70065A
Western Blot analysis of A431 and Jurkat cells using CFL1 Polyclonal Antibody at dilution of 1:600
Variation
Quantity
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Overview
Product Name
CFL1 Polyclonal Antibody
Catalog Number
RD70065A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.
Immunogen Information
Immunogen
Recombinant human Homeobox protein Cofilin-1 protein
Swissprot
P23528
Synonyms
18 kDa phosphoproteinCFL 1CFLCFL1COF1Cofilin 1Cofilin 1 non muscleCofilinCofilin non muscle isoformCofilin-1epididymis secretory protein Li 15HEL-S-15non-muscle isoformp18
Calculated MW
17 kDa
Observed MW
17 kDa
Applications
Reactivity
Human
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:1000
Concentration
2 mg/mL
Storage Buffer
PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas