CITED4 Polyclonal Antibody
Catalog Number
RD219707A
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using CITED4 Polyclonal Antibody at dilution of 1:65(×200)
Variation
Quantity
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Overview
Product Name
CITED4 Polyclonal Antibody
Catalog Number
RD219707A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this intronless gene belongs to the CITED family of transcriptional coactivators that bind to several proteins, including CREB-binding protein (CBP) and p300, via a conserved 32 aa C-terminal motif, and regulate gene transcription. This protein also interacts with transcription factor AP2 (TFAP2), and thus may function as a co-activator for TFAP2. Hypermethylation and transcriptional downregulation of this gene has been observed in oligodendroglial tumors with deletions of chromosomal arms 1p and 19q, and associated with longer recurrence-free and overall survival of patients with oligodendroglial tumors.
Immunogen Information
Immunogen
Synthetic peptide of human CITED4
Swissprot
Q96RK1
Synonyms
AU019445AW742964Cbp/p300 interacting transactivator 4cbp/p300 interacting transactivatorwith glu/asp rich carboxy terminal domain4Cbp/p300-interacting transactivator 4CITE4Cited4MRG 2MRG-2Mrg2MSG1 related protein 2MSG1-related protein 2Tra
Gene Accession
NP597724
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:30-1:150, ELISA 1:5000-1:10000
Concentration
0.9 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas