CK-19 Monoclonal Antibody
Catalog Number
RD70432A
Immunohistochemistry analysis of paraffin-embedded mouse stomach using CK-19 Monoclonal Antibody at dilution of 1:1000.
Immunohistochemistry analysis of paraffin-embedded rat stomach using CK-19 Monoclonal Antibody at dilution of 1:1000.
Variation
Quantity
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Overview
Product Name
CK-19 Monoclonal Antibody
Catalog Number
RD70432A
Clonality
Monoclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Mouse
Background
The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells. KRT19,one of type I keratins,is specifically expressed in the periderm,the transiently superficial layer that envelopes the developing epidermis. Due to its high sensitivity,KRT19 is the most used marker for detection of tumor cells disseminated in lymph nodes,peripheral blood,and bone marrow of breast cancer patients. This antibody,generated against full length KRT19 protein,also recognizes KRT17,another type I keratin homologous to KRT19. KRT17 is used as a marker for trauma.
Immunogen Information
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse Cytokeratin 19
Swissprot
P19001,Q63279
Synonyms
40 kDa keratin intermediate filamentCK 19CK-19CK19Cytokeratin 19Cytokeratin-19K19K1C19K1CSKeratin 19Keratin type I 40 kDKeratin type I 40kDKeratin type I cytoskeletal 19Keratintype I cytoskeletal 19Keratintype I40 kdKeratin-19KRT19MGC1
Applications
Reactivity
Mouse,Rat
Tested Applications
IHC
Conjugation
Unconjugated
Dilution
IHC 1:500-1:2000
Concentration
1.1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas