COPS8 Polyclonal Antibody
Catalog Number
RD81082A
Western blot analysis of extracts of various cell lines using COPS8 Polyclonal Antibody at dilution of 1:3000.
Variation
Quantity
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Overview
Product Name
COPS8 Polyclonal Antibody
Catalog Number
RD81082A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Immunogen Information
Immunogen
Recombinant fusion protein of human COPS8 (NP_006701.1).
Gene ID
10920
Swissprot
Q99627
Synonyms
COPS8COP9CSN8SGN8
Calculated MW
17 kDa/23 kDa
Observed MW
23 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.