CRTAM Polyclonal Antibody
Catalog Number
RD75133A
Western Blot analysis of 293T cell using CRTAM Polyclonal Antibody at dilution of 1:250
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CRTAM Polyclonal Antibody at dilution of 1:60
Variation
Quantity
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Overview
Product Name
CRTAM Polyclonal Antibody
Catalog Number
RD75133A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The CRTAM gene is upregulated in CD4 (see MIM 186940)-positive and CD8 (see CD8A; MIM 186910)-positive T cells and encodes a type I transmembrane protein with V and C1-like Ig domains. Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo.
Immunogen Information
Immunogen
Recombinant protein of human CRTAM
Swissprot
O95727
Synonyms
CD355Class I MHC restricted T cell associated moleculeClass-I MHC-restricted T-cell-associated moleculeCRTAMCRTAMCytotoxic and regulatory T cell moleculeCytotoxic and regulatory T-cell molecule
Calculated MW
45 kDa
Observed MW
Refer to Figures
Gene Accession
BC070266
Applications
Reactivity
Human
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas