CXCR4 Polyclonal Antibody
Catalog Number
RD71192A
Western Blot analysis of Mouse brain using CXCR4 Polyclonal Antibody at dilution of 1:1000.
Variation
Quantity
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Overview
Product Name
CXCR4 Polyclonal Antibody
Catalog Number
RD71192A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Immunogen Information
Immunogen
Synthesized peptide derived from the C-terminal region of human Fusin
Swissprot
P61073
Synonyms
C-X-C chemokine receptor type 4CD184CD184 antigenChemokine (C X C motif) receptor 4Chemokine CXC Motif Receptor 4CXC-R4CXCR-4CXCR4CXCR4D2S201EFB22FusinHM89HSY3RRLAP 3LAP3LCR1LESTRLeukocyte derived seven transmembrane domain receptorLeuk
Calculated MW
40 kDa
Observed MW
36 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IF,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IF 1:100-1:300, ELISA 1:40000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas