CYCS Polyclonal Antibody
Catalog Number
RD70094A
Western Blot analysis of Bovine heart using CYCS Polyclonal Antibody at dilution of 1:1000
Immunohistochemistry of paraffin-embedded Human pancreatic cancer using CYCS Polyclonal Antibody at dilution of 1:100
Variation
Quantity
For more information on our kits, please contact us at info@reddotbiotech.com
Overview
Product Name
CYCS Polyclonal Antibody
Catalog Number
RD70094A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Cytochrome c is a 12-15 kDa electron transporting protein located in the inner mitochondrial membrane. Upon apoptotic stimulation,cytochrome c can be released from mitochondria into cytoplasm,resulting in caspase-3 activation and apoptosis. Measurement of cytochrome c release from the mitochondria is useful for detection of the onset of apoptosis in cells. In addition,cytochrome c can also leave cells and be detectable in extra-cellular medium of apoptotic cells and serum of cancer patients. The level of serum cytochrome c may serve as a prognostic maker during cancer therapy.
Immunogen Information
Immunogen
Recombinant Human Cytochrome c protein
Swissprot
P99999
Synonyms
Cytochrome CSomaticCYCCytochrome CTHC4HCS.
Calculated MW
12 kDa
Observed MW
12 kDa
Applications
Reactivity
Human,Bovine
Tested Applications
WB,IHC
Conjugation
Unconjugated
Dilution
WB 1:1000-1:2000 IHC 1:100-1:200
Concentration
2 mg/mL
Storage Buffer
PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.