CYCS Polyclonal Antibody
Catalog Number
RD70247A
Western Blot analysis of various samples using CYCS Polyclonal Antibody at dilution of 1:1000.
Immunohistochemistry analysis of paraffin-embedded human lung cancer using CYCS Polyclonal Antibody at dilution of 1:1000.
Immunofluorescence analysis of paraffin-embedded mouse kidney using CYCS Polyclonal Antibody at dilution of 1:500.
Immunofluorescence analysis of paraffin-embedded mouse liver using CYCS Polyclonal Antibody at dilution of 1:500.
Immunohistochemistry analysis of paraffin-embedded Human Heart using CYCS Polyclonal Antibody.
Variation
Quantity
For more information on our kits, please contact us at info@reddotbiotech.com
Overview
Product Name
CYCS Polyclonal Antibody
Catalog Number
RD70247A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Cytochrome c is a 12-15 kDa electron transporting protein located in the inner mitochondrial membrane. Upon apoptotic stimulation,cytochrome c can be released from mitochondria into cytoplasm,resulting in caspase-3 activation and apoptosis. Measurement of cytochrome c release from the mitochondria is useful for detection of the onset of apoptosis in cells. In addition,cytochrome c can also leave cells and be detectable in extra-cellular medium of apoptotic cells and serum of cancer patients. The level of serum cytochrome c may serve as a prognostic maker during cancer therapy.
Immunogen Information
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse Cytochrome c
Swissprot
P99999,P62898,P62897
Synonyms
Cytochrome CSomaticCYCCytochrome CTHC4HCS.
Calculated MW
12 kDa
Observed MW
12 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC,IF
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:500-1:1000, IF 1:200-1:800
Concentration
1.5 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.