ELF3 Polyclonal Antibody
Catalog Number
RD219002A
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using ELF3 Polyclonal Antibody at dilution of 1:95(×200)
Variation
Quantity
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Overview
Product Name
ELF3 Polyclonal Antibody
Catalog Number
RD219002A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
Transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT]. Acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter. Also transactivates collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2 and TGM3 promoters. Represses KRT4 promoter activity. Involved in mediating vascular inflammation. May play an important role in epithelial cell differentiation and tumorigenesis. May be a critical downstream effector of the ERBB2 signaling pathway. May be associated with mammary gland development and involution. Plays an important role in the regulation of transcription with TATA-less promoters in preimplantation embryos, which is essential in preimplantation development (By similarity).
Immunogen Information
Immunogen
Fusion protein of human ELF3
Swissprot
P78545
Synonyms
E74 like factor 3E74 like factor 3 ets domain transcription factorE74 like factor 3 ets domain transcription factor epithelial specificE74 like factor 3 ETS domain transcription factor serine box epithelial specificE74-like factor 3Elf3ELF3Epitheli
Gene Accession
BC003569
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:300, ELISA 1:5000-1:10000
Concentration
1.68 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas