EXD2 Polyclonal Antibody

Catalog Number
RD218841A
Western blot analysis of Mouse brain tissue and Human cerebrum tissue lysates  using EXD2 Polyclonal Antibody at dilution of 1:700
Western blot analysis of Mouse brain tissue and Human cerebrum tissue lysates using EXD2 Polyclonal Antibody at dilution of 1:700
Immunohistochemistry of paraffin-embedded Human tonsil tissue  using EXD2 Polyclonal Antibody at dilution of 1:55(×200)
Immunohistochemistry of paraffin-embedded Human tonsil tissue using EXD2 Polyclonal Antibody at dilution of 1:55(×200)
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue  using EXD2 Polyclonal Antibody at dilution of 1:55(×200)
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using EXD2 Polyclonal Antibody at dilution of 1:55(×200)
Variation
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Overview
Circle
Product Name
EXD2 Polyclonal Antibody
Catalog Number
RD218841A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
Circle
Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks.
Immunogen Information
Circle
Immunogen
Fusion protein of human EXD2
Swissprot
Q9NVH0
Synonyms
4930539P14RikC14orf114C85658DKFZp781A0133DKFZp781L15100Exd2EXD2EXDL2Exonuclease 3''-5'' domain-containing protein 2Exonuclease 3''-5'' domain-like-containing protein 2exonuclease 3'-5' domain-like 2FLJ10738RGD1311087
Calculated MW
70 kDa
Observed MW
Refer to figures
Gene Accession
BC001962
Applications
Circle
Reactivity
Human, Mouse
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000
Concentration
0.96 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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