FKBP4 Polyclonal Antibody
Catalog Number
RD219050A
Western blot analysis of 231 and HepG2 cell lysates using FKBP4 Polyclonal Antibody at dilution of 1:900
Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using FKBP4 Polyclonal Antibody at dilution of 1:65(×200)
Variation
Quantity
For more information on our kits, please contact us at info@reddotbiotech.com
Overview
Product Name
FKBP4 Polyclonal Antibody
Catalog Number
RD219050A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
FKBP52 (FK506 binding protein 4) is a member of the immunophilin protein family that comprises intracellular protein effectors of immunosuppressive drugs,and it is known as a steroid receptor-associated protein. As a novel regulator of microtubule dynamics,FKBP52 is associated with the motor protein dynein and with the cytoskeleton during mitosis. FKBP52 is highly expressed in CNS regions susceptible to Alzheimer's,and plays a role in modulating toxicity of Abeta peptides. The protein can associate with the Tau function,and may help to decipher and modulate the events involved in Tau-induced neurodegeneration. In addition,FKBP52 is likely to play a role in growth and development of the male genitalia.
Immunogen Information
Immunogen
Fusion protein of human FKBP4
Swissprot
Q02790
Synonyms
51 kDa FK506-binding protein52 kDa FK506 binding protein52 kDa FK506-binding protein52 kDa FKBP59 kDa immunophilinFK506 binding protein 4FK506-binding protein 4FKBP 4FKBP 52FKBP 59FKBP-4FKBP-52FKBP4FKBP4FKBP51FKBP52 proteinFKBP59HBIHsp 5
Calculated MW
52 kDa
Observed MW
Refer to figures
Gene Accession
BC001786
Applications
Reactivity
Human, Mouse, Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:1000-1:5000, IHC 1:50-1:300, ELISA 1:5000-1:10000
Concentration
1.14 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas