Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
Immunogen Information
Immunogen
Synthesized peptide derived from human Flk-1 around the non-phosphorylation site of Tyr1214.
Swissprot
P35968
Synonyms
CD309CD309 antigenEC 2.7.10.1Fetal liver kinase 1FLK-1FLK1FLK1mousehomolog ofKdrKinase insert domain receptor (a type III receptor tyrosine kinase)Kinase insert domain receptorKRD1Ly73Protein tyrosine kinase receptor FLK1Protein-tyrosine ki
Calculated MW
152 kDa
Observed MW
145 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC-p,IF,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4