Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) catalyzes the phosphorylation of glyceraldehyde-3-phosphate during glycolysis. GAPDH participates in nuclear events including transcription, binding RNA, RNA transportation, DNA replication, DNA repair and apoptosis. Being stably and constitutively expressed at high levels in most tissues and cells, GAPDH is considered a housekeeping protein. It was widely used as a control for RT-PCR and also loading control in electrophoresis and Western blotting. GAPDH is normally expressed in cellular cytoplasm or membrane, but can occasionally translocate to the nucleus post modification such as S-nitrosylation.
Immunogen Information
Immunogen
Synthetic Peptide
Swissprot
P04406
Synonyms
Aging associated gene 9 proteinEpididymis secretory sperm binding protein Li 162ePG3PG3PDG3PDHGAPDGAPDHGlyceraldehyde 3 phosphate dehydrogenaseGlyceraldehyde-3-phosphate dehydrogenaseHEL S 162ePPeptidyl-cysteine S-nitrosylase GAPDH