GBA Polyclonal Antibody
Catalog Number
RD85084A
Western blot analysis of extracts of MCF-7 cells using GBA Polyclonal Antibody at dilution of 1:1000.
Variation
Quantity
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Overview
Product Name
GBA Polyclonal Antibody
Catalog Number
RD85084A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.
Immunogen Information
Immunogen
Recombinant fusion protein of human GBA (NP_000148.2).
Gene ID
2629
Swissprot
P04062
Synonyms
GBAGBA1GCBGLUC
Calculated MW
29 kDa/50 kDa/54 kDa/57 kDa/59 kDa
Observed MW
60 kDa
Applications
Reactivity
Human
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas