IDO2 Polyclonal Antibody
Catalog Number
RD218375A
Western blot analysis of Human fetal brain tissue and Human kidney tissue using IDO2 Polyclonal Antibody at dilution of 1:450
Immunohistochemistry of paraffin-embedded Human brain tissue using IDO2 Polyclonal Antibody at dilution of 1:45(×200)
Variation
Quantity
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Overview
Product Name
IDO2 Polyclonal Antibody
Catalog Number
RD218375A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
INDOL1 is also known as IDO2 (indoleamine 2,3-dioxygenase 2) and is a 407 amino acid protein that is expressed in various tissues, including liver, small intestine, spleen, placenta, thymus, lung, brain, kidney, colon and dendritic cells. INDOL1 is selectively inhibited by D-1MT (1-methyl-d-tryptophan), which also inhibits IDO (indoleamine 2,3-dioxygenase) and is significant because IDO expression causes suppression of T cell responses to tumors in dendritic cells. The inhibition of INDOL1 by D-1MT suggests a common function in immunomodulation. In the human INDOL1 gene, two single nucleotide polymorphisms have been detected which abolish the enzymatic function of INDOL1.
Immunogen Information
Immunogen
Full length fusion protein
Swissprot
Q6ZQW0
Synonyms
3-dioxygenase 23-dioxygenase-like protein 1EC 1.13.11.I23O2IDO 2IDO-2Ido2INDOL 1Indoleamine 2Indoleamine 23 dioxygenase 2Indoleamine 23 dioxygenase like 1 proteinIndoleamine 23 dioxygenase like protein 1Indoleamine pyrrole 23 dioxygenase l
Calculated MW
45 kDa
Observed MW
Refer to figures
Gene Accession
BC113496
Applications
Reactivity
Human
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas