IFITM2 Polyclonal Antibody
Catalog Number
RD218890A
Immunohistochemistry of paraffin-embedded Human tonsil tissue using IFITM2 Polyclonal Antibody at dilution of 1:25(×200)
Immunohistochemistry of paraffin-embedded Human brain tissue using IFITM2 Polyclonal Antibody at dilution of 1:25(×200)
Variation
Quantity
For more information on our kits, please contact us at info@reddotbiotech.com
Overview
Product Name
IFITM2 Polyclonal Antibody
Catalog Number
RD218890A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
IFITM2,also named as 1-8D,belongs to the CD225 family. It is an IFN-induced antiviral protein that mediates cellular innate immunity to at least three major human pathogens,namely influenza A H1N1 virus,West Nile virus (WNV),and dengue virus (WNV),by inhibiting the early step(s) of replication. IFITM2 induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner. It is overexpressed in colon carcinoma. IFITM2 is a novel pro-apoptotic gene that will provide new insights into the regulated cellular pathways to death. This antibody is specific to IFTIM2.
Immunogen Information
Immunogen
Fusion protein of human IFITM2
Swissprot
Q01629
Synonyms
1 8DDispanin subfamily A member 2cDSPA2cIFITM 2Interferon induced transmembrane protein 2 (1 8D)Interferon induced transmembrane protein 2Interferon inducible protein 1 8D
Gene Accession
BC009696
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:30-1:150, ELISA 1:5000-1:10000
Concentration
0.72 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas