IL6ST Polyclonal Antibody
Catalog Number
RD252510A
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using IL6ST Polyclonal Antibody at dilution of 1:40(×200)
Variation
Quantity
For more information on our kits, please contact us at info@reddotbiotech.com
Overview
Product Name
IL6ST Polyclonal Antibody
Catalog Number
RD252510A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17.
Immunogen Information
Immunogen
Fusion protein of human IL6ST
Swissprot
P40189
Synonyms
CD130CD130 antigenCDw130gp130GP130 RAPSIL 6R betaIL-6 receptor subunit betaIL-6R subunit betaIL-6R-betaIL-6RBIL6 STIL6RBIL6STInterleukin 6 receptor subunit betaInterleukin receptor beta chainInterleukin-6 receptor subunit betaInterleukin-6
Gene Accession
BC117402
Applications
Reactivity
Human, Mouse, Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:30-1:150, ELISA 1:5000-1:10000
Concentration
0.7 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.