IRF5 Polyclonal Antibody
Catalog Number
RD219512A
Western blot analysis of NIH/3T3 Hela Jurkat Hepg2 and A549 cell lysates using IRF5 Polyclonal Antibody at dilution of 1:250
Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using IRF5 Polyclonal Antibody at dilution of 1:25(×200)
Immunohistochemistry of paraffin-embedded Human tonsil tissue using IRF5 Polyclonal Antibody at dilution of 1:25(×200)
Variation
Quantity
For more information on our kits, please contact us at info@reddotbiotech.com
Overview
Product Name
IRF5 Polyclonal Antibody
Catalog Number
RD219512A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
IRF5,also named as SLEB10,contians one IRF tryptophan pentad repeat DNA-binding domain and belongs to the IRF family. I t is a transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection. It is activated by TLR7 or TLR8 signaling. Genetic variations in IRF5 are associated with susceptibility to inflammatory bowel disease type 14 (IBD14) and systemic lupus erythematosus type 10 (SLEB10).
Immunogen Information
Immunogen
Synthetic peptide of human IRF5
Swissprot
Q13568
Synonyms
Interferon regulatory factor 5Interferon regulatory factor 5 bone marrow variantIRF 5IRF-5Irf5IRF5SLEB10
Calculated MW
56 kDa
Observed MW
Refer to figures
Gene Accession
NP116032
Applications
Reactivity
Human, Mouse
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000
Concentration
0.7 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas