MAP2K5 Polyclonal Antibody
Catalog Number
RD84173A
Immunohistochemistry of paraffin-embedded Rat heart using MAP2K5 Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Human appendix using MAP2K5 Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Mouse heart using MAP2K5 Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunofluorescence analysis of MCF7 cells using MAP2K5 Polyclonal Antibody
Variation
Quantity
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Overview
Product Name
MAP2K5 Polyclonal Antibody
Catalog Number
RD84173A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described.
Immunogen Information
Immunogen
Recombinant fusion protein of human MAP2K5 (NP_660143.1).
Gene ID
5607
Swissprot
Q13163
Synonyms
MAP2K5HsT17454MAPKK5MEK5PRKMK5
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,IF
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200 IF 1:50-1:100
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas