NTRK1 Polyclonal Antibody
Catalog Number
RD266502A
Western blot analysis of extracts of various cell lines using NTRK1 Polyclonal Antibody at dilution of 1:500.
Immunohistochemistry of paraffin-embedded Rat liver using NTRK1 Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Human stomach using NTRK1 Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Mouse brain using NTRK1 Polyclonal Antibody at dilution of 1:100 (40x lens).
Variation
Quantity
For more information on our kits, please contact us at info@reddotbiotech.com
Overview
Product Name
NTRK1 Polyclonal Antibody
Catalog Number
RD266502A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.
Immunogen Information
Immunogen
A synthetic peptide of human NTRK1 (NP_002520.2).
Gene ID
4914
Swissprot
P04629
Synonyms
NTRK1MTCTRKTRK1TRKATrk-Ap140-TrkA
Calculated MW
77 kDa/83 kDa/86 kDa/87 kDa
Observed MW
140 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000 IHC 1:50-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas