PARP1 Monoclonal Antibody
Catalog Number
RD85515A
Western Blot analysis of 1) Hela, 2) 293T, 3) Jurkat cells using PARP1 Monoclonal Antibody at dilution of 1:2000.
Variation
Quantity
For more information on our kits, please contact us at info@reddotbiotech.com
Overview
Product Name
PARP1 Monoclonal Antibody
Catalog Number
RD85515A
Clonality
Monoclonal
Purification Method
Protein A purification
Isotype
IgG
Host
Mouse
Background
This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
Immunogen Information
Immunogen
Synthetic Peptide
Swissprot
P09874
Synonyms
ADP-ribosyltransferase diphtheria toxin-like 1ADPRT 1ADPRTADPRT1APOPAINARTD1NAD(+) ADP-ribosyltransferase 1PARPPARP-1PARP1PARP1Poly [ADP-ribose] polymerase 1Poly ADP ribose polymerase 1Poly[ADP-ribose] synthase 1PPOLSCA1
Observed MW
116 kDa
Applications
Reactivity
Human
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:1000-3000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.