PAX5 Polyclonal Antibody
Catalog Number
RD219303A
Immunohistochemistry of paraffin-embedded Human prost at e cancer tissue using PAX5 Polyclonal Antibody at dilution of 1:30(×200)
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PAX5 Polyclonal Antibody at dilution of 1:30(×200)
Variation
Quantity
For more information on our kits, please contact us at info@reddotbiotech.com
Overview
Product Name
PAX5 Polyclonal Antibody
Catalog Number
RD219303A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
PAX5,also named B-cell specific activator protein (BSAP),is a member of the highly conserved paired box (PAX)-domain family of transcription factors. PAX5 is essential in normal B-cell lymphopoiesis. It is expressed in pro-B,pre-B and mature B lymphocytes but not in plasma cells. PAX5 is a common target in leukemogenesis of B-ALL ( B-lineage acute lymphoblastic leukemia) along with CDKN2A. Owing to its frequent deletion in B-ALL,PAX5 could be used as one of the molecular markers in diagnosis and monitoring of the disease. This antibody is specific to PAX5. It will not cross react with other PAX members.
Immunogen Information
Immunogen
Synthetic peptide of human PAX5
Swissprot
Q02548
Synonyms
B cell lineage specific activatorB cell lineage specific activator proteinB cell specific activator proteinB cell specific transcription factorB-cell-specific transcription factorBSAPEBB-1KLPPaired box 5Paired box gene 5 (B cell lineage specific
Gene Accession
NP057953
Applications
Reactivity
Human, Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:30-1:150, ELISA 1:5000-1:10000
Concentration
0.84 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas